Posts Tagged ‘renal function’

July 9, 2012

Pediatric Heart failure and worsening renal function: Association with outcomes after heart transplant


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Renal function has been shown to be a risk factor for death while waiting for heart transplant and following transplantation in the pediatric population. Little is known about the effects of a deterioration of function from the time of listing to transplantation. This study was designed to determine the effects of worsening renal function during […]

No Comments Posted in Cardiac Transplantation
August 14, 2011

The ORION Study: Comparison of Two Sirolimus-Based Regimens versus Tacrolimus and Mycophenolate Mofetil in Renal Allograft Recipients


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This randomized controlled trial in de novo renal transplant recipients compared a standard immunosuppressive protocol of daclizumab induction, tacrolimus, mycophenolate mofetil (MMF) and steroids, to either: sirolimus and tacrolimus, with tacrolimus discontinued by four months post-transplant, or sirolimus and MMF. The sirolimus and MMF group was stopped early due to a high incidence of acute […]

No Comments Posted in Renal Transplantation