Posts Tagged ‘rituximab’

November 18, 2011

Reduction of alloantibodies via proteosome inhibition in cardiac transplantation


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The approach to desensitization varies between cardiac transplant centers.  This pilot study by Kobashigawa et al, explores a new approach in desensitization attempts in patients refractory to an IVIg/rituximab combination therapy.  Bortezomib successfully reduced cPRA in the majority of patients with an acknowledged increase risk of infection.

No Comments Posted in Cardiac Transplantation
June 18, 2011

Monitoring Infection with Epstein–Barr Virus among Seromismatch Adult Renal Transplant Recipients


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PTLD is often serious and difficult to treat post-transplant.  Antiviral prophylaxis is often used in EBV D+/R- transplant patients and monitoring is done in many centers for early detection of viremia.  In this single-center cohort study, EBV mismatched kidney transplant patients were monitored.  A small number of patients with persistent viremia in the first year […]

No Comments Posted in Transplant Infectious Disease