Posts Tagged ‘skin cancer’

August 17, 2012

Sirolimus and Secondary Skin-Cancer Prevention in Kidney Transplantation


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This randomized controlled trial assessed whether sirolimus would prevent further skin cancers in patients who have had a first squamous-cell skin cancer post-renal transplant. Patients were either continued on their calcineurin inhibitor or were switched to sirolimus. Freedom from a second skin cancer was longer with sirolimus. Switching to sirolimus earlier after a fist skin […]

No Comments Posted in Renal Transplantation
April 14, 2012

Randomized Controlled Trial of Sirolimus for Renal Transplant Recipients at High Risk for Nonmelanoma Skin Cancer

Several randomized controlled trials have shown lower rates of non-melanoma skin cancer among patients who receive sirolimus from the time of transplant. This study randomized previously transplanted patients who had previously had at least one skin cancer to either continue on their usual immunosuppression or change their calcineurin inhibitor to sirolimus. There were fewer new […]

No Comments Posted in Renal Transplantation
August 14, 2011

Increased Incidence and Mortality Associated With Skin Cancers After Cardiac Transplant.


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This multicenter study (based on 32 US centers contributing to the Cardiac Transplant Research Database), provides detailed skin cancer risk information about cardiac transplant recipients that is less influenced by geography or ethnic factors than single-center data.  Such risk factor data can help direct preventive and treatment strategies to the most at-risk individuals.

No Comments Posted in Cardiac Transplantation