Posts Tagged ‘survival’

October 6, 2013

The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Official Adult Heart Transplant Report—2013; Focus Theme: Age


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The 30th adult heart transplant ISHLT report is based on data submitted on 110,486 heart transplants in recipients of all ages (including 99,008 adults) by 407 centers worldwide since 1982 through June 30, 2012, with follow-up until June 30, 2012.

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September 8, 2013

The urgent priority for transplantation is to trim the waiting list


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This thought provoking editorial by Dr. Lynne Warner Stevenson provides commentary on ineffective waitlist strategies and the need for change.

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September 7, 2013

Heart transplantation outcomes from cardiac arrest-resuscitated donors.


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CPR requiring donors, utilized and identified in the UNOS database tended to be younger and had a mean CPR time of 20 minutes. Despite resucitation times, use of carefully selected donors requiring CPR did not impact recipient outcomes including patient and graft survival. The authors hypothesize that ischemic preconditioning may influence the non-inferior outcomes.

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July 11, 2013

HeartWare ventricular assist system for bridge to transplant: Combined results of the bridge to transplant and continued access protocol trial.


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The pivotal ADVANCE Clinical Trial was a multicenter clinical trial to evaluate the HeartWare HVAD System for BTT in patients with advanced heart failure in the United States. This publication reports the analysis of combined data from the 140 BTT patients plus 192 patients from the continued access protocol (CAP) who were monitored to outcome […]

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July 9, 2013

Prophylactic implantable cardioverter defibrillator treatment in patients with end-stage heart failure awaiting heart transplantation.


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This observational study supports the CCS recommendations of ICD consideration in transplant eligible patients. In this study, ICDs appear to be associated with a reduction in all-cause mortality in both primary and secondary prevention compared to those without an ICD despite a median time on the waiting list of only 8 months (estimated 1-year: 88±3% vs […]

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June 21, 2013

Long-term outcome in patients treated with combined heart and liver transplantation for familial amyloidotic cardiomyopathy


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Currently, adults with congenital heart disease account for 3% of heart and nearly 40% of heart_lung transplant recipients worldwide. Ten years of patient outcomes were reviewed between 2001 and 2011. This single center, high volume center demonstrated comparable early and mid-term outcomes in adult congenital heart patients to general outcomes when careful recipient selection was […]

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June 21, 2013

Characterization of 25+ year survivors of cardiac transplantation


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This single center study reviews the echocardiographic, hemodynamic and clinical characteristics of long-term survivors post heart transplant. The investigators demonstrated a significant burden of cardiac allograft vasculopathy in the setting of preserved graft function. Diastolic parameters were significantly altered.

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June 21, 2013

Preoperative Assessment of High Risk Candidates to Predict Survival Following Heart Transplantation.


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Alternative wait list strategies for heart transplant recipients have not yet been popularized in Canada. This article from Columbia University explores the concept of matching ñhigh riskî recipients with marginal donor organs. Survival analysis revealed lower post-HTx survival in high risk recipients (82.2 versus 87.4 % at 1-yr; 59.8 versus 76.3 % at 5-yrs post-HTx; […]

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April 1, 2013

OPTN/SRTR 2011 Annual Data Report: heart.


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This annual report from the Organ Procurement and Transplantation Network provides an American update with temporal trends in cardiac transplant activity.

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April 1, 2013

Fifth INTERMACS annual report: Risk factor analysis from more than 6,000 mechanical circulatory support patients.


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The 5th annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes and analyzes the first 6 years of patient and data collection. The current analysis includes more than 6000 patients and updated risk factors for continuous flow pumps. Among continuous flow pumps, actuarial survival is 80% at 1 year and 70% […]

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