Posts Tagged ‘transfusions’

January 28, 2013

Effects of HLA-Matched Blood Transfusion for Patients Awaiting Renal Transplantation


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Preventing the development of anti-HLA antibodies is an important step in improving access to transplantation. In this non-randomized retrospective study, patients who received red blood cell transfusions from donors who were closely matched for class I antigens were less likely to develop anti-HLA antibodies than patients who received randomly selected donors. These findings are intriguing, […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
January 28, 2013

Effects of HLA-Matched Blood Transfusion for Patients Awaiting Renal Transplantation


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Preventing the development of anti-HLA antibodies is an important step in improving access to transplantation. In this non-randomized retrospective study, patients who received red blood cell transfusions from donors who were closely matched for class I antigens were less likely to develop anti-HLA antibodies than patients who received randomly selected donors. These findings are intriguing, […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
February 23, 2012

Red blood cell transfusions in children awaiting heart transplantation


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Although not studied in the pediatric population, red blood cell (RBC) transfusions may be beneficial in children awaiting transplantation. However, the use of RBC transfusions has been associated with increasing the risk of allosensitization. This retrospective, single center study examined the role of both RBC transfusions and erythropoietin in hospitalized children awaiting transplant who where […]

No Comments Posted in Cardiac Transplantation
November 18, 2011

Blood Transfusions in Organ Transplant Patients: Mechanisms of Sensitization and Implications For Prevention


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Sensitization to mismatched HLA can result from transplantation, pregnancy, and blood transfusions. As the extent of sensitization of a transplant recipient increases, the likelihood of finding an acceptable donor expressing HLA to which they have not generated HLA antibodies to decreases. Although advances have been made in desensitization protocols, little attention has been paid to […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation