Posts Tagged ‘voriconazole’

January 28, 2013

Increased incidence of cutaneous squamous cell carcinoma in lung transplant recipients taking long-term voriconazole


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Voriconazole is commonly prescribed for treatment of fungal infections in lung transplant recipients. Typically patients are treated for several weeks with this medication. This retrospective study of 120 lung transplant recipients compared the incidence of squamous cell carcinoma in patients with and without voriconazole use. Squamous cell carcinomas (SCC) developed in 39.5% of patients who […]

No Comments Posted in Lung Transplantation, Transplant Infectious Disease
January 28, 2013

Increased incidence of cutaneous squamous cell carcinoma in lung transplant recipients taking long-term voriconazole


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Voriconazole is commonly prescribed for treatment of fungal infections in lung transplant recipients. Typically patients are treated for several weeks with this medication. This retrospective study of 120 lung transplant recipients compared the incidence of squamous cell carcinoma in patients with and without voriconazole use. Squamous cell carcinomas (SCC) developed in 39.5% of patients who […]

No Comments Posted in Lung Transplantation, Transplant Infectious Disease
October 30, 2012

Emergence of Aspergillus calidoustus Infection in the Era of Posttransplantation Azole Prophylaxis.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Invasive aspergillosis is an important cause of morbidity after lung transplant. The majority of lung transplant centers use universal anti-mould prophylaxis for 3-6 months after transplant. This may be extended further depending on the patient’s level of immunosuppression. Resistant fungi can emerge with such prolonged prophylaxis. This paper reports a series of lung transplant patients […]

No Comments Posted in Transplant Infectious Disease
August 17, 2012

High cumulative dose exposure to voriconazole is associated with cutaneous squamous cell carcinoma in lung transplant recipients


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Immunosuppressive therapies used in lung transplant recipients increase the risk of cutaneous squamous cell carcinoma (SCC). This retrospective study hypothesized that voriconazole, used for treatment of invasive fungal infections and known to have phototoxic side effects, may be an additional risk factor for SCC in lung transplant recipients. Cumulative exposure to voriconazole was calculated for […]

No Comments Posted in Lung Transplantation