August 2, 2013

Urinary-Cell mRNA Profile and Acute Cellular Rejection in Kidney Allografts


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The gold standard fro diagnosing acute rejection remains biopsy. A non-invasive test that could reliably diagnose rejection would be an important step forward. In this study, a set of three different RNA molecules in the urine of renal transplant recipients showed a high degree of sensitivity for acute cellular rejection, and distinguished it from antibody-mediated rejection. It was not affected by the type of induction immunosuppression the patients had received.

Renal Transplantation

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