Posts Tagged ‘ischemia-reperfusion injury’

July 10, 2013

A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death.


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Various techniques are being explored to optimize hearts and the assess organ function before transplantation. This may ultimately increase the number of organs available for transplantation. In this experimental model of DCD, an ex vivo heart perfusion strategy using initial reperfusion with a tepid adenosine-lidocaine cardioplegia and continuous myocardial perfusion minimized myocardial injury and improved […]

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June 21, 2013

Renal Transplantation After Ex Vivo Normothermic Perfusion: The First Clinical Study


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The standard method of kidney preservation uses an acellular solution at low temperatures, either cold storage or with machine perfusion. This article describes an system which adapts cardioplumonary bypass technology to perfuse the kidney with a oxygenated blood prior to implantation. In this uncontrolled study, kidneys that underwent ex vivo normothermic perfusion had a low […]

No Comments Posted in Renal Transplantation