Posts Tagged ‘Ventricular Assist Device’

June 21, 2013

Cost-Effectiveness of Ventricular Assist Device Therapy as a Bridge to Transplant in Comparison to Non-Bridged Cardiac Recipients.


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This article provides contemporary Canadian data for the cost-effectiveness of BTT-VAD versus unbridged HTx recipients. The sensitivity analysis estimated a 59%, 54% and 43% chance of BTT-VAD therapy being cost-effective for high, medium and low risk patients at a willingness to pay of $100,000/LY.

No Comments Posted in Cardiac Transplantation
June 21, 2013

A Prospective, Multicenter Study of Ventricular Assist Device Infections

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This prospective study demonstrated that the incidence of ventricular assist device related infection continues to burden approximately 20% of implanted patients in the era of smaller continuous flow devices. There was an associated increase in one year mortality.

No Comments Posted in Cardiac Transplantation
June 21, 2013

Clinical outcomes after ventricular assist device implantation in adults with complex congenital heart disease.

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This single center case series from the Texas Heart Institute describes the clinical challanges and outcomes of 6 patients with complex CHD who underwent VAD implantation with a variety of devices. A future article (epub) is pending in the same journal (JHLT) which may provide further insight into this challenging patient population: Heart transplantation for […]

No Comments Posted in Cardiac Transplantation
April 1, 2013

Fifth INTERMACS annual report: Risk factor analysis from more than 6,000 mechanical circulatory support patients.

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The 5th annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes and analyzes the first 6 years of patient and data collection. The current analysis includes more than 6000 patients and updated risk factors for continuous flow pumps. Among continuous flow pumps, actuarial survival is 80% at 1 year and 70% […]

No Comments Posted in Cardiac Transplantation
April 1, 2013

OPTN/SRTR 2011 Annual Data Report: heart.

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This annual report from the Organ Procurement and Transplantation Network provides an American update with temporal trends in cardiac transplant activity.

No Comments Posted in Cardiac Transplantation
April 1, 2013

The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: Executive summary.

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The Executive summary is provided. This is a comprehensive review of the currently recommended interdisciplinary management considerations in mechanical circulatory support patients.

No Comments Posted in Cardiac Transplantation
January 28, 2013

Morbidity and Mortality in Heart Transplant Candidates Supported with Mechanical Circulatory Support. Is Reappraisal of the Current UNOS Thoracic Organ Allocation Policy Justified?

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Within the cardiac transplant community there has been much discussion regarding the evolution in technology of mechanical circulatory support and the impact on organ allocation. This article published in Circulation suggests transplant candidates supported with contemporary continuous flow LVADs have favorable waiting list outcomes. In contrast outcomes worsen significantly once a serious LVAD-related complication occurs. […]

No Comments Posted in Cardiac Transplantation
January 28, 2013

Morbidity and Mortality in Heart Transplant Candidates Supported with Mechanical Circulatory Support. Is Reappraisal of the Current UNOS Thoracic Organ Allocation Policy Justified?

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Within the cardiac transplant community there has been much discussion regarding the evolution in technology of mechanical circulatory support and the impact on organ allocation. This article published in Circulation suggests transplant candidates supported with contemporary continuous flow LVADs have favorable waiting list outcomes. In contrast outcomes worsen significantly once a serious LVAD-related complication occurs. […]

No Comments Posted in Cardiac Transplantation
September 19, 2012

Quality of Life and Left Ventricular Assist Device Support

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This thorough literature review describes current indicators of quality of life in ventricular assist device patients and addresses cognitive function, sleep disturbance, emotional distress, sexual activity and end of life issues. A “must read” for mechanical circulatory support team members.

No Comments Posted in Cardiac Transplantation
December 19, 2011

Usefulness of Two-Dimensional Echocardiographic Parameters of the Left Side of the Heart to Predict Right Ventricular Failure After Left Ventricular Assist Device Implantation

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Right ventricular failure (RVF) following left ventricular assist device (LVAD) implantation can be a challenging if not catastrophic event.  The risk assessment strategies for right ventricular failure vary in complexity. This article by Mancini et al, demonstrates that the preoperativeLVechocardiographic RVF score, focusing on only left-sided parameters could accurately predict the development of RVF after […]

No Comments Posted in Cardiac Transplantation